October 16
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1975 – Rahima Banu, a 2-year old girl from the village of Kuralia in Bangladesh, is the last known person to be infected with naturally occurring smallpox.
1987 – Paul Holc becomes the youngest Human on Earth to have an organ transplant, receiving a new heart at just three hours old.
2005 – China becomes the first country to approve the commercial production of a gene therapy.
2005 – Shenzhou 6, China's second manned space flight, lands after orbiting the Earth for five days.