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'''Synthehol''' (a portmanteau of "synthesized" and "alcohol") is a chemical variant of [[alcohol]]. It appears to have the same taste and smell as "real" alcohol to most individuals, but none of the deleterious effects associated with alcohol for most [[humanoid]]s, such as debilitating intoxication, addiction, and alcohol [[poison]]ingpoisoning. Most humanoids have an [[enzyme]] which breaks down the alcohol-like compounds in synthehol. According to [[Data]], synthehol's "intoxicating effects can be easily dismissed".
It is a regular ingredient in the drinks served on [[Starfleet]] [[starship|vessels]] and [[starbase]]s, but some [[bartender]]s bartenders like [[Guinan]] and [[Quark]] kept a supply of alcoholic {{MA|Beverage|beverage}}s for customers requesting such.
The slight chemical difference between synthehol and real alcohol is an annoyance to lovers of alcoholic beverages such as [[Robert Picard]] and [[Montgomery Scott]]. Robert Picard believed that synthehol corrupted his brother [[Jean-Luc Picard]]'s taste for [[wine]], while Jean-Luc believed it gave one a greater appreciation for the real thing. [[Captain]] Scott was able to differentiate alcohol from synthehol when he drank a glass of [[scotch]] in the {{USS|Enterprise|NCC-1701-D|-D}}'s [[Ten Forward]] lounge. He found the taste revolting, and he let the young bartender who served him know it.
On [[https://memory-alpha.fandom.com/wiki/Ferenginar Ferenginar Ferenginar]], Quark was known as "[[The Synthehol King]]".
In [[2369]], during his brief tenure as [[Grand Nagus]], Quark was approached by [[Nava]], who wanted to introduce synthehol to the [[Gamma Quadrant]]. Quark thought it sounded like a "very lucrative opportunity".
In early [[2371]], during a downturn in business due to the threat of the [[Dominion]], Quark had a sale on synthehol.
On at least two occasions, [[Seven of Nine]] has become intoxicated after drinking synthehol, as her [[Borg]] implants were not designed to process it. She suffered similar symptoms to those that [[alcohol]] has on [[Human]]s.
In [[2375]], when the [[Kadi]] [[ambassador]] [[Tomin]] visited {{USS|Voyager}}, he attended a reception at which he drank some syntheholic beverages. It was later realized that Kadi physiology lacks the enzyme which breaks down the alcohol-like substance in synthehol, which caused him to become drunk and attempt to woo Seven of Nine. He later passed out, and [[The Doctor]] was able to remove the synthehol with Seven's [[nanoprobe]]s.
