Barclay's Protomorphosis Syndrome
An artificial disease accidentally created by Dr. Beverly Crusher. While attempting to cure Lieutenant Reginald Barclay of Urodelan flu, she used a synthetic T-cell to activate the gene that would fight off the infection. An anomaly in Barclay's genetic structure caused the T-cell to mutate and activate all of his dormant genes, including his latent introns. Interaction between the Urodelan flu caused the T-cell to become an airborne virus.
The initial symptoms of the disease include abnormal behavior, irritability, chills, fever, and paranoia. The virus causes the awakened genes to become aggressive, and alter the body until it physically regresses into an earlier form of its species. In short, the body de-evolves.
The syndrome was cured by using amniotic fluid to create a retrovirus that eliminated the effects.