April 15
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1912 – The ocean liner RMS Titanic strikes an iceberg and sinks on her maiden voyage from the United Kingdom to the United States.
2005 - The Soyuz-TMA 6 was launched by Russian from Baikonur Cosmodrome carrying Expedition 10 crew to the ISS (International Space Station). The crew included Sergei Krikalev (who broke the record for total time in space during this mission), John Phillips and Robert Vittori.
2006 - Anthony Atala and team at Wake Forest Baptist Medical Center publish their success in transplanting the first laboratory-grown organs into human patients.